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However, our data impressively demonstrate the geneticinstability in this chromosomal region.
2
Oxidative DNA damage seems to contribute to geneticinstability observed in cancer.
3
Background: Latent geneticinstability has been associated with an increased risk for several cancers.
4
However, their inherent geneticinstability hinders application for prophylactic purposes.
5
Defects in DNA damage responses may underlie geneticinstability and malignant progression in melanoma.
6
Infected tax-expressing CD4+ lymphocytes accumulated cellular defects characteristic of geneticinstability.
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In addition, geneticinstability is commonly seen.
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This work also suggests how deficiencies in DNA damage detection systems can result in geneticinstability and cancer.
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In small compartments, geneticinstability, which confers a selective disadvantage for the cell, can spread by random drift.
10
Background: Colorectal cancer develops through two main geneticinstability pathways characterized by distinct pathologic features and clinical outcome.
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In addition, we describe geneticinstability and exceptional phenotypic changes that accompany the evolution of these new LSC populations.
12
Thus, small compartments protect against mutations in tumor suppressor genes or oncogenes but promote the emergence of geneticinstability.
13
P53 inactivation determines a condition of geneticinstability, justifying the subsequent susceptibility to acquire mutations of different other genes.
14
For some unknown reason ( geneticinstability?
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Conclusion: Latent geneticinstability as measured by the comet assay is associated with an increased estimated relative risk of bladder cancer.
16
ROS can stimulate cell proliferation, promote geneticinstability, and induce adaptive responses that enable cancer cells to maintain their malignant phenotypes.