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Использование термина genetic instability на английском
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However, our data impressively demonstrate the geneticinstability in this chromosomal region.
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Oxidative DNA damage seems to contribute to geneticinstability observed in cancer.
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Background: Latent geneticinstability has been associated with an increased risk for several cancers.
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However, their inherent geneticinstability hinders application for prophylactic purposes.
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Defects in DNA damage responses may underlie geneticinstability and malignant progression in melanoma.
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Infected tax-expressing CD4+ lymphocytes accumulated cellular defects characteristic of geneticinstability.
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In addition, geneticinstability is commonly seen.
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This work also suggests how deficiencies in DNA damage detection systems can result in geneticinstability and cancer.
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In small compartments, geneticinstability, which confers a selective disadvantage for the cell, can spread by random drift.
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Background: Colorectal cancer develops through two main geneticinstability pathways characterized by distinct pathologic features and clinical outcome.
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In addition, we describe geneticinstability and exceptional phenotypic changes that accompany the evolution of these new LSC populations.
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Thus, small compartments protect against mutations in tumor suppressor genes or oncogenes but promote the emergence of geneticinstability.
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P53 inactivation determines a condition of geneticinstability, justifying the subsequent susceptibility to acquire mutations of different other genes.
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For some unknown reason ( geneticinstability?
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Conclusion: Latent geneticinstability as measured by the comet assay is associated with an increased estimated relative risk of bladder cancer.
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ROS can stimulate cell proliferation, promote geneticinstability, and induce adaptive responses that enable cancer cells to maintain their malignant phenotypes.