There is no specific ultrasound prenatal diagnosis and no identified genetic locus.

The broad genetic locus heterogeneity renders mutation screening time-consuming and expensive.

Conclusion: We report identification of a genetic locus for familial mesial temporal lobe epilepsy.

This genetic locus may contain determinants that play a crucial role in male gametogenesis by P. falciparum.

To our knowledge, this is the first genome-scan report to identify a genetic locus harboring a gout-susceptibility gene.

The SAP gene has been identified as the genetic locus responsible for X-linked lymphoproliferative disease, a fatal immunodeficiency.

We report the identification of a second genetic locus, bride of sevenless (boss) required for the development of R7.

We find that a genetic locus on mouse chromosome 12 influences the affinity maturation of antibodies as well as autoantibody production.

The results, for the first time, suggest that the possibility of pleiotropic genetic effect may be controlled by a major genetic locus.

In recent years pleiotropy, the phenomenon of one genetic locus influencing several traits, has become a widely researched field in human genetics.

To overcome the broad genetic locus heterogeneity, a strategy of DNA pooling with consecutive massively parallel resequencing (MPR) was devised.

In addition to the well-known contribution of BRCA, we demonstrate that a genetic locus on the X-chromosome contributes to ovarian cancer risk.

We mapped the genetic locus to chromosome 15q22.2-24.2 and show that the disease is caused by mutations in SMAD3.

The authors examined six families for linkage to the previously identified genetic locus (IBGC1) located on chromosome 14q.

Genetic crossing of the lines suggests that the refractory trait is inherited as a single dominant genetic locus.