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Despite several reports of linked loci, major gene identification has been elusive.
2
In addition, we identified MOBP and SCFD1 as new associated risk loci.
3
Linkage analysis is used to map genetic loci using observations on relatives.
4
Risk loci in several populations have been identified with genetic linkage analysis.
5
However, the effects that we observe are subtle and variable between loci.
1
However, the mitochondrial locus provided greater resolution on more recent evolutionary events.
2
They said the nation state is the ultimate locus of people's identity.
3
Previously, we created a backcross population suitable for mapping the responsible locus.
4
Fallion thought for a long moment, wondering if Stalker had a locus.
5
No prognostic value was associated with LOH at any one specific locus.
1
Impact: These findings may help to identify geneticregions associated with IMPC risk.
2
This study aimed to determine the geneticregions associated with strain effects on lesion area.
3
In particular, the oldest pre-epidemic isolates carry phage-associated geneticregions not previously reported in S. Enteritidis.
4
The genomic positions of recombinant and mobile geneticregions were partially linked, suggesting their concurrent occurrence.
5
Further research on these geneticregions will enhance our understanding of the genetic basis of natural menopause.
1
Pathogenicity is restored to wild-type levels in strains with reconstitution of the genomiclocus.
2
Hence, CAPTURE provides a versatile platform to study genomiclocus-regulating chromatin composition in a mammalian genome.
3
To facilitate both gene-specific and systems biology oriented research, our database provides the means to analyze individual genes or an entire genomiclocus.
4
We further observed Firre localization across five distinct trans-chromosomal loci, which reside in spatial proximity to the Firre genomiclocus on the X chromosome.
1
Their ability to readily manipulate the native genomicloci is particularly advantageous.
2
However, processing different databases and searching among millions of genomicloci is not trivial.
3
Currently miRBase is their primary repository, providing annotations of primary sequences, precursors and probable genomicloci.
4
Pseudo-polyploidy at relevant genomicloci sets the stage for gaining additional mutations at the locus of interest.
5
This study was aimed at identifying the genomicloci linked to exercise participation in males and females.
1
The aim of the study is detection of Y-sequences of DNA level, calculation of mosaicism and its cytogeneticlocation.
1
Here, we report the nucleotide sequence and chromosomallocus of the mouse Hes-3 gene.
2
Homozygosity mapping with SNPs was performed for identification of the chromosomallocus for the disease.
3
These molecules undergo homologous recombination with the corresponding chromosomallocus to generate targeted alterations of the host genome.
4
Linkage to the chromosomallocus 13q31-q32 has previously been reported in a large French family.
5
Herein, we identified a novel TAL1-regulated super-enhancer controlling the GIMAP locus, which resides within an insulated chromosomallocus in T-ALL cells.
1
Linkage analysis is used to map geneticloci using observations on relatives.
2
A GWAS meta-analysis identified 68 geneticloci controlling platelet size and number.
3
Previous studies have identified many geneticloci for refractive error and myopia.
4
For most geneticloci which have been tested, there have been inconsistent results.
5
We aimed to identify geneticloci that are associated with bone mineral density.
1
DNAloci that interact with the target RNA are identified using high-throughput DNA sequencing.
2
In gene regulation, proteins function as members of protein complexes to recognize chromosomal target DNAloci.
3
These findings suggest that longevity is partly determined by epistatic interactions involving these three mt DNAloci.
4
We have developed a measure of genetic distance, DSW, which is appropriate for the analysis of highly polymorphic DNAloci.
5
A marked variation in number and localization of r DNAloci but no correlation between the numbers of rDNA clusters and genome size was found.
Usage of genetic locus in English
1
There is no specific ultrasound prenatal diagnosis and no identified geneticlocus.
2
The broad geneticlocus heterogeneity renders mutation screening time-consuming and expensive.
3
Conclusion: We report identification of a geneticlocus for familial mesial temporal lobe epilepsy.
4
This geneticlocus may contain determinants that play a crucial role in male gametogenesis by P. falciparum.
5
To our knowledge, this is the first genome-scan report to identify a geneticlocus harboring a gout-susceptibility gene.
6
The SAP gene has been identified as the geneticlocus responsible for X-linked lymphoproliferative disease, a fatal immunodeficiency.
7
We report the identification of a second geneticlocus, bride of sevenless (boss) required for the development of R7.
8
We find that a geneticlocus on mouse chromosome 12 influences the affinity maturation of antibodies as well as autoantibody production.
9
The results, for the first time, suggest that the possibility of pleiotropic genetic effect may be controlled by a major geneticlocus.
10
In recent years pleiotropy, the phenomenon of one geneticlocus influencing several traits, has become a widely researched field in human genetics.
11
To overcome the broad geneticlocus heterogeneity, a strategy of DNA pooling with consecutive massively parallel resequencing (MPR) was devised.
12
In addition to the well-known contribution of BRCA, we demonstrate that a geneticlocus on the X-chromosome contributes to ovarian cancer risk.
13
We mapped the geneticlocus to chromosome 15q22.2-24.2 and show that the disease is caused by mutations in SMAD3.
14
The authors examined six families for linkage to the previously identified geneticlocus (IBGC1) located on chromosome 14q.
15
Genetic crossing of the lines suggests that the refractory trait is inherited as a single dominant geneticlocus.