Undesired limitation of the utility of a technology due to trade-offs in its technical design.
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The possible effect on human health is a problem of current debate.
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Background: Contact allergy is a major public health problem in industrialized countries.
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Objective: Asthma is a major public health problem with considerable economic impact.
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Background: Hypertension is becoming a major public health problem in developing countries.
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The Prime Minister said all governments had a serious structural budget problem.
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Therefore, the aim is to solve the problem of stock DNA limitation.
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Current designs have one limitation: They work only for the color red.
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Space limitation leads to competition between benthic, sessile organisms on coral reefs.
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Within-person change in functional limitation was not reliably associated with social activity.
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A major limitation of these measures is their dependence on disease prevalence.
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Don't think that it happens by chance or that it's a shortcoming.
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Only sheep in the Republic go unidentified; a shortcoming exposed by foot-and-mouth.
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Sometimes this is the result of art, sometimes of a natural shortcoming.
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Yet this is a race where the slightest shortcoming can be multiplied.
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Squire Bartley had a growing sense of shortcoming in his farming operations.
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This is due to a simple technical limitation: There's no way to put the camera and the display screen in the same spot.
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A major technical limitation has been the absence of methods allowing long-term measurement of kidney tissue oxygen tension (Po₂) in unrestrained animals.
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Large changes to and from zero, might be related to technical limitations.
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Balancing players' demands with technical limitations is the name of the game.
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Higher concentrations of urea could not be tested due to technical limitations.
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The "depth" of this structure has only technological limitations.
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In the meantime, however, it's not cultural factors, but rather technological limitations that are limiting this new weapon.
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Structural variations are the greatest source of genetic variation, but they remain poorly understood because of technological limitations.
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Based on this work, the practical advantages and current technological limitations to single-particle cryoEM at 100 keV are considered.
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In fairness, this is not generally due to weaknesses in the ideas, but more to do with technological limitations.
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Was this absence down to software limitations in 1939 or were we just trying to confuse all visiting pilots?
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Smaller is almost always better in the world of computer technology, but there are technical limits.
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These technical limits liberate our brains from interference.
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The MICEX and RTS bourses were twice forced to call brief suspensions of trading as sharp gains exceeded technical limits.
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Authors' conclusions: We identified relatively few, mostly small studies with short-term follow-up and design limitations.
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Careful review of published trials of these interventions reveals design limitations that contributed to their inconclusive findings.
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When the vibrations are dampened, the resulting motion is kept within the design limitations of the structure of the aircraft.
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Among the possible design limitations of CAR-T cells for cancer are unwanted tonic (antigen-independent) signaling and off-target activation.
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We emphasize the linking of clinical results to molecular mechanisms, discuss study design limitations, and offer some recommendations for future directions.
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But hardware limitations might limit its initial success as a major player in the mobile streaming world.
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And all of a sudden, the hardware limitations that stood in the way of VR weren't a problem anymore.
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Many such devices already ship with Linux rather than Windows, in part because of hardware limitations and also because skipping Windows keeps costs down.