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Our results reveal further differences and similarities between human iPSCs and hESCs.
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Neural cells derived from iPSCs can be produced in a large quantity.
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FTD-iPSCs were fated to cortical neurons, the cells most affected in FTD.
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Most of the edited cells show characteristics of iPSCs and genome integrity.
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Nonetheless, recent studies provide some evidence of immunological benefit for using autologous iPSCs.
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Our results reveal further differences and similarities between human iPSCs and hESCs.
2
Neural cells derived from iPSCs can be produced in a large quantity.
3
FTD-iPSCs were fated to cortical neurons, the cells most affected in FTD.
4
We demonstrate that both ESC-CMs and iPSC-CMs can facilitate comparable cardiac repair.
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Most of the edited cells show characteristics of iPSCs and genome integrity.
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An elephant iPScell engineered to contain those mutations would theoretically be capable of producing woolly mammoth sperm.
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EB formation and exposure to ColIV both induced iPScell differentiation into cells that expressed cardiovascular and hematopoietic markers.
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However, variable genetic and phenotypic characterization of many existing iPScell lines limits their potential use for research and therapy.
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The field of regenerative medicine is therefore primed to adopt and incorporate iPScell-based advancements as a next generation stem cell platforms.
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Typically, production of inducedpluripotentstemcells requires direct contact with feeder cells.
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They call the cells inducedpluripotentstemcells, or iPS cells for short.
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The model uses human brain endothelial cells derived from inducedpluripotentstemcells.
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Teams are working to fine-tune these so-called inducedpluripotentstemcells or iPS cells.
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Recently, investigators have exploited molecular techniques to generate inducedpluripotentstemcells from patients' somatic cells.
Usage of induced pluripotent stem cell in English
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Here, we studied bioenergetics in an inducedpluripotentstemcell-based model of the disease.
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These findings were supported by differentiation experiments using BOS patient-derived inducedpluripotentstemcell lines.
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Nanog facilitates embryonic stem cell self-renewal and inducedpluripotentstemcell generation during the final stage of reprogramming.
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Human embryonic stem cells and especially patient specific inducedpluripotentstemcell-derived cardiomyocytes are well established as cardiac disease model..
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Here we report the generation of a human inducedpluripotentstemcell line from a BA patient using episomal vectors.
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Using cell surface capture technology, the cell surface N-glycoproteome of human- inducedpluripotentstemcell derived hepatic endoderm cells was assessed.
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This was verified in prefrontal cortex and - inducedpluripotentstemcell-derived neurons for the L-type calcium channel (CACNA1C) risk locus.
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They said they are now working to generate the so-called inducedpluripotentstemcell or iPS cells to match a variety of diseases.
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The epigenetic dynamics of inducedpluripotentstemcell (iPSC) reprogramming in correctly reprogrammed cells at high resolution and throughout the entire process remain largely undefined.
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Inducedpluripotentstemcell (iPSC) models of HD provide an opportunity to study the mechanisms underlying disease pathology in disease-relevant patient tissues.