Meanings of lead to discontinuation in English

Hepatic complications have become common and may lead to discontinuation of treatment and significant morbidity.

Liver dysfunction can lead to discontinuation of potentially life-saving chemotherapy in nearly one-half of the patients with exacerbation of HCV infection.

No drug-related events leading to discontinuation were noted in the linezolid group.

It is the combination of toxicity with modest efficacy that led to discontinuation.

Other reasons for discontinuation and adverse events not leading to discontinuation were also comparable.

Severe side effects leading to discontinuation of treatment occurred in 9% of patients.

No potential adverse events led to discontinuation of IGD.

The outcomes were clinical response, colectomy free rate, and severe adverse events leading to discontinuation of therapy.

The most common adverse events were gastrointestinal and generally occurred early, were self-limiting and infrequently led to discontinuation.

In 35% of trials, results led to discontinuation of the drug which otherwise would have been continued indefinitely.

A total of 13 subjects (46.4 %) experienced adverse events that led to discontinuation of study drug.

Of the 21 subjects, three (14%) had an increase in HIV viral load of more than 0.5 log leading to discontinuation of ribavirin in one.