Hepatic complications have become common and may leadtodiscontinuation of treatment and significant morbidity.
2
Liver dysfunction can leadtodiscontinuation of potentially life-saving chemotherapy in nearly one-half of the patients with exacerbation of HCV infection.
3
No drug-related events leadingtodiscontinuation were noted in the linezolid group.
4
It is the combination of toxicity with modest efficacy that ledtodiscontinuation.
5
Other reasons for discontinuation and adverse events not leadingtodiscontinuation were also comparable.
6
Severe side effects leadingtodiscontinuation of treatment occurred in 9% of patients.
7
No potential adverse events ledtodiscontinuation of IGD.
8
The outcomes were clinical response, colectomy free rate, and severe adverse events leadingtodiscontinuation of therapy.
9
The most common adverse events were gastrointestinal and generally occurred early, were self-limiting and infrequently ledtodiscontinuation.
10
In 35% of trials, results ledtodiscontinuation of the drug which otherwise would have been continued indefinitely.
11
A total of 13 subjects (46.4 %) experienced adverse events that ledtodiscontinuation of study drug.
12
Of the 21 subjects, three (14%) had an increase in HIV viral load of more than 0.5 log leadingtodiscontinuation of ribavirin in one.