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In this study we determine systemic comorbidities associated with lichensclerosus in men.
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Bullous lichensclerosus is a rare variant that can occur in both genital and extragenital LS.
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Men with lichensclerosus were more likely to have hypertension, hyperlipidemia and diabetes, and to use tobacco products.
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A 2-hit mechanism implicating local and systemic factors for lichensclerosus related urethral stricture disease development and progression is hypothesized.
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Results: Of the 1,151 men in the database 81 (7.0%) were noted to have lichensclerosus related urethral stricture disease.
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Conclusions: Lichensclerosus related urethral stricture disease is associated with chronic systemic diseases.
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Purpose: Lichensclerosus is a chronic, inflammatory skin condition of the genitalia of unknown origin that accounts for nearly 10% of urethral stricture disease.