Corneal epithelial stem cells are thought to be at the limbus.

Trabeculectomy was performed through a limbus-based incision in nine eyes of nine patients.

When epithelial defects extended beyond the limbus, they were healed by conjunctival epithelium.

Fibroblasts that appeared at the wound site exhibited marked CO activity around the limbus.

In limbus-destroying eye injuries, corneal transplants nearly always fail.

GR receptor mRNAs were demonstrated in spiral ligament cells, spiral limbus cells, and spiral ganglion cells.

The proximal structures had greater diameters nasally, whereas the SVP was larger in the inferior limbus.

Free grafts from the superotemporal limbus of the same eye were used to cover the exposed sclera.

These results indicate that only limited proliferative capacity of corneal epithelium remains in the absence of limbus.

This suggests that epithelial cell renewal at the limbus was accelerated in the presence of disturbed reepithelialization.

Ocular examination revealed sparing of the limbus.

To the best of our knowledge, no reports exist on allogeneic corneoscleral limbus tissue transplantation for treatment of these.

Depth of the anterior chamber at the temporal limbus was graded as a percentage fraction of peripheral corneal thickness.

Conclusions: Taken together these results, explain in part the immunosuppressive features of this cell population obtained from the human limbus.

The stem cells are produced by the limbus, an area surrounding the cornea, and eventually differentiate and drift where needed.

The isolated cells transdifferentiate into corneal epithelial-like cells in conditioned medium containing corneal limbus soluble factors, including their specific marker, keratin12.