Meanings of mediate gene in English

These correlations may be explained by chromosomal destabilization, which can mediate gene amplification and can result in cellular lethality.

Thus, pharmacological GCs mediate gene expression by favoring GR homodimer occupancy at classic palindromic sites at the expense of monomeric binding.

MBD2 is a subunit of the NuRD complex that is postulated to mediate gene repression via recruitment of the complex to methylated DNA.

In this study, we investigated the potential of this vector, pEPI-eGFP, to mediate gene transfer in hematopoietic progenitor cell lines and primary human cells.

In initial studies, the optimal conditions for retrovirus- mediated gene transfer were determined.

Cortical administration of Rp-8-Cl-cAMPS attenuated the experience-dependent activation of CRE- mediated gene transcription.

Hepatocytes that self-assemble into spheroids can be transduced through adenovirus- mediated gene transfer.

This Review focuses primarily on E2A- mediated gene regulation during B-lymphocyte development.

The triplet codon repeats lead to heterochromatin- mediated gene silencing and loss of frataxin.

Adenoviral- mediated gene delivery targeted its expression mainly to intestinal epithelial cells.

Reduction of β-catenin availability using small interfering RNA- mediated gene silencing inhibited ERKs phosphorylation.

Adenovirus- mediated gene therapy has been limited by immune reaction and target genes selection.

These new developments in formulation technology enhance the potential for polymeric nanoparticle- mediated gene therapy.

These results combined suggest that Nrf3 is a negative regulator of ARE- mediated gene expression.

These data provide insights into GATA-1- mediated gene regulation in vivo.

Nuclear receptor- mediated gene expression is regulated by corepressors and coactivators.