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Meanings of mediate mdr in English
We have no meanings for "mediate mdr" in our records yet.
Usage of mediate mdr in English
1
We conclude that resistance to anthracyclines and vinca alkaloids in childhood relapsed ALL is not due to P-glycoprotein mediated MDR.
2
Our study provides the first direct evidence that enhancement of the JNK pathway down-regulates P-glycoprotein and reverses P-glycoprotein- mediated MDR in cancer cells.
3
Overall, we found that peptide HX-12C reverses ABCB1- mediated MDR through interacting with ABCB1 and blocking its function without affecting the transporter's expression and cellular localization.