Significados de mediate mdr em inglês

We conclude that resistance to anthracyclines and vinca alkaloids in childhood relapsed ALL is not due to P-glycoprotein mediated MDR.

Our study provides the first direct evidence that enhancement of the JNK pathway down-regulates P-glycoprotein and reverses P-glycoprotein- mediated MDR in cancer cells.

Overall, we found that peptide HX-12C reverses ABCB1- mediated MDR through interacting with ABCB1 and blocking its function without affecting the transporter's expression and cellular localization.