We are using cookies This website uses cookies in order to offer you the most relevant information. By browsing this website, you accept these cookies.
There was no increase in resistance to methylmethanesulfonate and N-hydroxyethyl-N-chloroethylnitrosourea.
2
In primary cell cultures, heterozygous cells also display reduced proliferation rates and moderate sensitivity to methylmethanesulfonate.
3
Bleomycin and methylmethanesulfonate also induced strand cleavage in a synthetic oligonucleotide duplex even without thermal treatment.
4
We also analyzed sensitivity to methylmethanesulfonate, observing little dependence of resistance on MGMT and persistent variability in cytotoxicity in the presence of O6-BG.
5
In comparison with data obtained with the methylating agent methylmethanesulfonate we further conclude that the assumption of DNA adducts being oversensitive biomarkers is adduct-specific.