Plasma DHT concentrations in rats subjected to transient neonatalhypothyroidism remained unaltered.
2
Apparent neonatalhypothyroidism and malformations were not observed in the offspring of either group.
3
The effect of neonatalhypothyroidism on spermatogenesis was studied in Wistar rats of different age groups.
4
All other groups of rats subjected to transient neonatalhypothyroidism had consistently low titres of plasma and TIF testosterone.
5
Conclusion: Continuing antithyroid drug therapy throughout pregnancy prevents postpartum recurrence of Graves' hyperthyroidism without resulting in neonatalhypothyroidism or malformations.
6
We have previously demonstrated that neonatal and transient neonatalhypothyroidism modulates Leydig, Sertoli, and germ cell numbers, sex steroids and androgen binding protein concentration.
7
A consistent increase in Leydig cell number was seen in puberal rats subjected to transient neonatalhypothyroidism but decreased in 60 days hypothyroid rats.
8
Neonatalhypothyroidism was induced by adding 0.02% methimazole in the drinking water from day 9 of gestation, and continually until 14 days old.