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Meanings of unbound drug in English
We have no meanings for "unbound drug" in our records yet.
Usage of unbound drug in English
1
The percentage of unbound drug was slightly higher in both moderately impaired cohorts.
2
The pharmacodynamic relationship between unbound drug concentration and QT prolongation was fit by a simple linear model.
3
Arthritic rats exhibited lower plasma and ISF albumin concentrations and reduced clearances of unbound drug to explain pharmacokinetic profiles.
4
The net effect of chronic inflammation was an elevation of the C max and area under the plasma concentration-time curve (AUC) of unbound drug.
5
A trend was observed toward more severe hematologic toxicity with the 3-hour schedule (P =.053), consistent with increased exposure to unbound drug.
6
Unbound drug is the pharmacodynamically relevant concentration.