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Significados de constitutive nf en inglés
Aún no tenemos significados para "constitutive nf".
Uso de constitutive nf en inglés
1
ConstitutiveNF-kB is often found in some types of cancers, contributing to oncogenesis and tumor progression.
2
This knowledge is key to develop strategies for prevention and treatment of constitutiveNF-kB-driven inflammatory diseases and cancers.
3
Inhibition of constitutiveNF-kappaB activation by expression of IkappaBalpha super-repressor reduced proliferation of the basal-like subtype cell lines.
4
In mice, deficiency of miR-146a results in hematolymphoid cancer at advanced ages as a consequence of constitutiveNF-kB activity.
5
We show in this manuscript that for melanoma there is a strong relationship between expression of the LTbeta-R and constitutiveNF-kappaB transcriptional activity.
6
Aberrant and constitutiveNF-kB activation are frequently reported in numerous tumor types, making its inhibition an attractive target for the treatment of certain cancers.
7
Experimental introduction of CARD11 coiled-coil domain mutants into lymphoma cell lines resulted in constitutiveNF-kappaB activation and enhanced NF-kappaB activity upon antigen receptor stimulation.
8
However, neither the subtypes of breast cancer cells with constitutiveNF-kappaB activation nor the molecular mechanisms leading to its constitutive activation have been clearly defined.
9
BAY 11-7082 (3.5 microM) inhibited constitutiveNF-kappaB activity in the three cell lines whereas the anticancer agents did not.
10
Taken together, these data suggest that suppression of constitutiveNF-kappaB activity by BAY 11-7082 may be a useful treatment for MDR leukemias.
11
These findings demonstrate the physiological relevance of the NF-kappaB2 p100 precursor protein in limiting the potentially detrimental effects of constitutiveNF-kappaB2 signaling in lymphocytes.
12
The identification of a FOXP3-miR-146-NF-kB axis provides an underlying mechanism for disruption of miR-146 family member expression and constitutiveNF-kB activation in breast cancer cells.