Significados de dependent inactivation en inglés

Depolarization depends on a presynaptic calcium current, which displays only slight voltage- dependent inactivation.

We also examined the rapid time- dependent inactivation process that mediates rectification at positive potentials.

The inactivation time constants decreased with positive shifts in membrane potential favouring a voltage- dependent inactivation.

Expression of a mutant Snail protein that is resistant to GSK-3β- dependent inactivation also promotes EndMT.

K+ currents showed voltage- dependent inactivation which was half-maximal at -25 mV.

The resulting cyclin D1- dependent kinase initiates the phosphorylation- dependent inactivation of the retinoblastoma tumor suppressor protein.

In addition, activity- dependent inactivation was observed with sodium as the charge carrier through the calcium channels.

The activity- dependent inactivation depends on divalent cation influx.

A Cl- channel with large single-unit conductance and characteristic voltage- dependent inactivation was studied on cultured human fibroblasts.

This reduction in driving force for calcium currents eliminated divalent cation influx and abolished the activity- dependent inactivation.

Margatoxin-sensitive currents showed voltage- dependent inactivation.

Flux- dependent inactivation that arises from functional coupling between the inner gate and the selectivity filter is widespread in ion channels.

Two potential mechanism-based inhibitors were tested with recombinant taxadiene synthase but neither provided time- dependent inactivation nor afforded more than modest competitive inhibition.

A new inactivator of the enzyme, 6-chloro-3-hydroxyanthranilic acid, was synthesized and was shown to exhibit time- dependent inactivation.

We therefore conclude that the dependence of activity- dependent inactivation on divalent cation influx cannot be attributed to the known form of calcium-dependent inactivation.

Their voltage- and Ca(2+)- dependent inactivation kinetics are slower than in other tissues but the underlying molecular mechanisms are not yet understood.