Both regions demonstrate similar relative DNase I sensitivities within a given tissue.
2
Using DNase-seq data improved predictions of tissue-specific expression compared with motifs alone.
3
The DNA nature of these filaments was determined by digestion with DNase.
4
DNase activity in the original seminal plasma was abolished after HFF co-incubation.
5
Nuclear GAPDH is tightly bound, resisting extraction by DNase or salt treatment.
1
We compared the effect of rhDNase and HS on cationic proinflammatory mediators in CF sputum.
2
In summary, we were unable to show that rhDNase or HS promote airway inflammation in CF.
3
When changes in mediator levels with daily rhDNase were compared with alternate-day rhDNase and HS, no significant differences were detected.
4
The double-blind, 14 day study showed no significant improvement in pulmonary function but some patients may have improved after longer administration of rhDNase.
Uso de dnase i en inglés
1
Both regions demonstrate similar relative DNaseI sensitivities within a given tissue.
2
Precise binding regions were investigated by DNAseI protection studies.
3
In situ oligo ligation technique was used to identify specific DNaseI-type DNA cleavage.
4
Gel shift and DNaseI analyses demonstrated that IclR binds to its own promoter.
5
DNA-melting and DNaseI footprinting experiments were also performed.
6
Results of DNaseI footprinting provide strong support for bent recognition helices in leucine zipper protein-DNA complexes.
7
The DHS map was developed by sequencing individual DNaseI cleavage sites using massively parallel sequencing technologies.
8
The chromatin structure of the chick alpha 2(I) collagen gene was probed with DNaseI.
9
Targeting NFATc1 with specific small hairpin RNA inhibits DNaseI hypersensitive site formation and down-regulates target gene expression.
10
Addition of these amino acids strongly affects the extent of the region protected by CodY in DNaseI footprints.
11
The NBS is well protected during DNaseI footprinting assays and specifically binds proteins in electrophoretic mobility shift assays.
12
DNaseI footprinting experiments indicated that the nuclease specifically binds to its cleavage sites on the DNA under non-catalytic conditions.
13
Here we investigated the transcriptional regulation of the gene, using DNaseI hypersensitivity assay followed by luciferase reporter gene assay.
14
DNaseI hypersensitivity and chromatin immunoprecipitation assays demonstrated that the lack of expression was correlated with a closed chromatin structure.
15
To assess whether 3D chromatin organization changes during this transition, we established Capture Hi-C with target-sequence enrichment of DNaseI hypersensitive sites.
16
ENCODE also generated the genome-wide mapping of eleven histone marks, one histone variant, and DNaseI hypersensitivity sites in seven cell lines.