A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery.
Taken together, these data suggest that KGF is an important endogenousmediator of normal hair follicle growth, development, and differentiation.
2
Future experiments and clinical trial may help defining circumstances under which inhibiting or augmenting endogenousmediators may be a helpful adjunctive therapy for sepsis.