Unfortunately, the program doesn't quite work in the way the producers intended.
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How a rogue weapons program created the new American way of war.
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The program faced criticism even before the health reform law was passed.
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Backers hope to expand the program to 50 countries within five years.
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Singapore Airlines will join the test program later this year, it said.
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TBI modulates the neuronal excitability resulting in propagation of a neuronal activity-driven geneexpressionprogram.
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All living creatures change their geneexpressionprogram in response to nutrient availability and metabolic demands.
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Our study provides molecular-level understanding of a geneexpressionprogram in B. abortus that is downstream of σE1.
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Notch induces a broad antiapoptotic geneexpressionprogram that protects against intrinsic, as well as extrinsic, apoptosis pathways.
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Together, these findings indicate that Setd1b serves as maternal effect gene through regulation of the oocyte geneexpressionprogram.
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The geneticprogram for the development of the TMJ remains poorly understood.
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It must have been a geneticprogram, but officially he's an accident.
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For Wilson, the geneticprogram is key to understanding human development on all levels.
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The survival and death of lymphoid cells is under the control of a geneticprogram.
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Conclusion: LKB1 and Notch share a common geneticprogram in the liver, and regulate bile duct morphogenesis.
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Mitotic phosphorylation of YAP controls a unique transcriptionalprogram in pancreatic cells.
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These results define a transcriptionalprogram that controls diversification of a paramorphic pair.
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STAT3 hijacks a subset of ER enhancers to drive a distinct transcriptionalprogram.
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HOTAIR overexpression is sufficient to activate the ER transcriptionalprogram even under hormone-deprived conditions.
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The cellular response to hypoxia relies on the activation of a specific transcriptionalprogram.
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This reconstruction allowed us to identify candidate regulatory genecircuit elements underlying T cell fate decision making.
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Using a synthetic genecircuit, we show that a transcriptional activator driven by yeast cell-cycle promoters propagates transcriptional oscillations with substantial damping.
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Regulatory genecircuits enable stem and progenitor cells to detect and process developmental signals and make irreversible fate commitment decisions.
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Accurately predicting noise propagation in gene networks is crucial for understanding signal fidelity in natural networks and designing noise-tolerant genecircuits.
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The ability to create designer aTFs will enable applications including dynamic control of cell metabolism, cell biology and synthetic genecircuits.
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What is less clear is how these changes interact with trans-acting changes occurring elsewhere in the geneticcircuit.
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In a normal cell, powerful geneticcircuits regulate cell division and cell death.
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We found 364 candidate obesity-regulating cis elements and geneticcircuits in different cell types.
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Cells act like tiny computers, and finally, scientists are figuring out what makes their geneticcircuits blink on and off.
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This finding leads to the proposal that mathematicians study geneticcircuits to find new geometries for which structure theorems may exist.
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Further, P-HIPSTer enables discovery of previously unappreciated cellularcircuits that act on human-infecting viruses and provides insight into experimentally intractable viruses.
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It is envisaged that analysing the cellular 'circuitry' of ongoing molecular networks will become a powerful clinical tool in patient management.
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Tongue myogenesis follows a similar regulatoryprogram to that for limb myogenesis.
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In January 2013, U.S. District Court Judge James Boasberg issued an injunction halting the IRS's regulatoryprogram.
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The analysis of time course data on cell differentiation indicated a shift in the regulatoryprogram associated with Pioneer-like transcription factors during differentiation.
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Despite recent advances in our understanding of the gene regulatoryprogram directing steatosis, how it is orchestrated at the chromatin level is unclear.
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Comparison of medulloblastoma regulatory elements with those of the developing brain reveals that these tumors engage a developmental regulatoryprogram to drive OTX2 transcription.
Uso de gene program en inglés
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However, the heart retains the ability to return to the "fetal" geneprogram.
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Despite the advance, there is no therapy available to reverse the already committed geneprogram.
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In contrast, exposure to arterial laminar flow induces a geneprogram that confers a largely antiadhesive, antithrombotic effect.
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Finally, real-time quantitative PCR revealed an age-dependent recapitulation of the fetal geneprogram, consistent with a myopathic process.
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Finally, we show that OXT acts directly on OXTRs on adipocytes to suppress the white-to-beige transition geneprogram.
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NF-kappaB regulates the fetal geneprogram and PPARalpha-regulated gene expression during cardiac hypertrophy and induces atrophy in skeletal muscle.
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The absence of calsarcin-1 also activated a hypertrophic geneprogram, despite the absence of hypertrophy, and enhanced the cardiac growth response to pressure overload.
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In response to stress signals, postnatal cardiomyocytes undergo hypertrophic growth accompanied by activation of a fetal geneprogram, assembly of sarcomeres, and cellular enlargement.
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We propose that in failing heart muscle at a certain point the fetal geneprogram is no longer sufficient to support cardiac structure and function.
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The HDAC3-PROX1 module controls the expression of a geneprogram regulating lipid homeostasis, and hepatic-specific ablation of either component increases triglyceride content in liver.
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Nrf2 is the key transcription factor for cytoprotective geneprograms.
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The liver coordinates the expression of geneprograms that control glucose absorption, storage, and secretion.
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Unstable angina may be a clinical analogue to ischemic preconditioning, and involve activation of geneprograms.
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In this review, we will discuss how TCR-signaling events coordinate cellular metabolism and specialization geneprograms in T cells.
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Transcription factors are essential nuclear proteins that trigger the expression of geneprograms required for long-term functional and structural plasticity changes.
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These findings provide further support for an important role of LXRs in the coordinated regulation of lipid metabolic and inflammatory geneprograms in macrophages.