Longevity is a polygenic trait in which genetic predisposition is particularly important.
2
We conclude ACL rupture is a moderately heritable highly polygenic complex trait.
3
Unlinked background genes were accounted for by fitting a polygenic variance component.
4
We therefore examined whether known polygenic BD risk alleles are associated with ADHD.
5
Therefore, additional knowledge needs to be generated, particularly for polygenic traits.
Uso de multigenic en inglés
1
Etiology is thought to involve complex, multigenic interactions and possible environmental contributions.
2
Taken together, these results indicate that MeLiM swine is a model for human multigenic diseases.
3
Here, we present sequencing data of a family with a potentially multigenic origin of CHD.
4
Background: Psychiatric disorders are multigenic diseases with complex etiology that contribute significantly to human morbidity and mortality.
5
Although poorly understood, it has long been recognized that host regulation of virus-associated disease severity is multigenic.
6
The mode of inheritance remains to be determined, but it appears to be complex and potentially multigenic.
7
Hypertension is a multigenic disorder in which abnormal counterregulation between dopamine and Ang II plays a role.
8
Moreover, our study highlights the need for new approaches allowing a multigenic analysis to clarify the genotype-phenotype correlation in TRB.
9
They probably constitute the entire chs multigenic family of this fungus, as revealed by careful analysis of six euascomycetes genomes.
10
The mandibles of F(1) hybrids are mostly intermediate between parental phenotypes as expected for a complex multigenic character.
11
Thirteen single-copy genes were used for phylogenetic analysis; the resulting trees are largely consistent with those inferred from multigenic plastid datasets.
12
Unlike other diseases, such as cystic fibrosis, that are caused by defects in one specific gene, asthma is a so-called multigenic disease.
13
Acquisition of a metastatic phenotype by breast cancer cells includes alternations of multigenic programs that permit tumor cells to metastasize to distant organs.
14
Highly transcribed genes were present in multigenic salt-soluble chromatin domains ranging in length from 30 to over 150 kb.
15
It is considered a complex multigenic and multifactorial disorder that results from disturbed interactions between the immune system and commensal bacteria of the gut.
16
These results indicate that resistance to DX and MTX in human OS cell lines is a multigenic process involving gene copy number and expression changes.