One patient who underwent LT is waiting for ENU due to post-cryotherapy complication.
2
Here we review progress in ENU mutagenesis screening, with an emphasis on creating mouse models for human disorders.
3
Our results demonstrate that the expression of differentiation antigens in ENU-induced experimental neurinomas parallels the results reported for human neurinomas.
4
ENU is a toxin and carcinogen as well as a mutagen, and strains differ in their susceptibility to its effects.
5
We report on a battery of behavioral screening tests that successfully identified several neurobehavioral mutants among a large-scale ENU-mutagenized mouse population.
1
Here we introduce a method for real-time identification of N-ethyl-N-nitrosourea-induced mutations that cause phenotypes in mice.
Uso de neu en inglés
1
We used a leaky stochastic accumulator to model the neu …
2
Amplification and overexpression of the neu gene have been found in several human adenocarcinomas.
3
Together these studies indicate that p185neu expression is a common feature of human lung tumors.
4
Down-modulation of the normal cell-surface neu protein was inefficient.
5
Survival of animals was significantly prolonged after immunization with vaccines encoding neu together with the costimulatory molecules.
6
Here, we compared an H. ducreyi neuA mutant to its wild-type parent in several models of pathogenesis.
7
This study demonstrates that intramuscular or intradermal injections of rat neuNT full-length DNA into mice generate anti-p185 autoantibodies.
8
We have examined the expression of the neu gene in human non-small cell lung carcinomas using immunoprecipitation and immunohistochemistry.
9
The neu is found over-expressed in 20-30% of human breast tumors.
10
The recombinant neu differentiation factor-alpha 2 isoform had no significant biological effects in either full or deep partial thickness burns.
11
Retrospective studies suggest that HER2-neu status is a powerful independent prognostic factor in T1a,b node-negative breast cancer.
12
We tested possible down-modulating effects of these monoclonal antibodies on SKBR-3 mammary tumor cells, which express high levels of wild-type human neu protein.
13
In this study, we screened overlapping peptides of the entire neu protein and identified six new epitopes recognized by vaccine-induced neu-N-derived T cells.
14
Earlier studies have shown that neu transgenic mice exhibit immune tolerance to the neu-expressing tumors similar to what is observed in patients with cancer.
15
The transforming genes of 6 other transformants derived from 3 sarcomas did not contain ras family or neu transforming genes.
16
No CTL response was evoked in either IL-12-treated or DNA-vaccinated mice, whereas an anti-rat p185neu antibody response was evident in the latter.