Last month Biogen said a fourth patient in Europe had developed PML.
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However, the basis for such a structural role of PML is unknown.
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The average number of infusions received before diagnosis of PML was 25.
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In particular, PML and p53 showed considerable potential as independent prognostic markers.
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Dozens of patients undergoing treatment with Tysabri have been diagnosed with PML.
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Allogeneic and peptide vaccines and granulocyte-macrophage colony-stimulating factor are also being evaluated.
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However, the increase of expression level varied among the PBSC and granulocyte products.
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Results: Fifty-one transcripts were chosen to be preferentially expressed by each granulocyte subtype.
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The binding curve data suggested that there are two monocyte and granulocyte populations.
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These antibodies are directed against different enzymes located in granulocyte granules.
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The IC preparation did also induce an oxidative burst response in PMNs.
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The circulating PMN of control subjects did not show a spontaneous O2-.
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Despite this adaptation, their bactericidal capability remains limited when compared with PMNs.
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To induce apoptosis PMNs were cultured overnight while Jurkat cells were UV-treated.
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Conclusions: CPB primes the inflammatory system causing pulmonary PMN sequestration without lung injury.
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Mature granulocytes show a markedly limited life span and rapidly undergo apoptosis.
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So they took Anna in to give granulocytes -white blood cells.
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To resolve infections, an adequate number of functional granulocytes is required.
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With few exceptions, treatment resulted in a prompt increase in granulocytes and eosinophiles.
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These studies indicate that bcl-2 is involved in regulating apoptosis in maturing granulocytes.
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In contrast, lipid A was a potent inducer of the PMNL response.
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The studies reported here were undertaken to determine whether influenza virus could replicate within PMNL.
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Both host- and virus-specific proteins were produced within PMNL.
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Conclusion: Activated PMNLs enhance production of leukocyte MPs with increased adhesion molecules in patients with sepsis.
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This study analyzed the ability of mucosally administered bacterial components to activate IL-6 and PMNL responses.
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Both polymorphonuclearcell infiltration and increased epithelial apoptosis are seen in gastric mucosa in the presence of Helicobacter pylori infection.
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However, the chemotactic response of both polymorphonuclearcells and T lymphocytes in response to CXCL12 is increased.
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H. pylori colonization is followed by infiltration of the gastric mucosa by polymorphonuclearcells, macrophages and lymphocytes.
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The outcome of CDAD was not influenced by the number of circulating polymorphonuclearcells and CD4+ cells.
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Polymorphonuclearcells (neutrophils) play an important role in the systemic inflammatory response syndrome and the development of sepsis.
Uso de polymorphonuclear leukocyte en inglés
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Similar shifts were seen in the graphs of polymorphonuclearleukocyte elastase and thrombin-antithrombin complex.
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Total white blood cell, polymorphonuclearleukocyte, and immature neutrophil counts rose significantly in response to sepsis.
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Peripheral blood mature and immature polymorphonuclearleukocyte (PMN) cell counts were determined on Wright-stained blood smears.
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Analysis of variance indicated that the means for polymorphonuclearleukocyte and immature neutrophil counts were significantly higher in survivors.
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It has not been shown, however, that the polymorphonuclearleukocyte increase caused by nuclein has made phagocytosis more active.
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As a result of these effects, LXA4 stable analogs inhibited the ability of bacteria-infected epithelia to direct polymorphonuclearleukocyte movement.
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Moreover, no differences were observed in polymorphonuclearleukocyte-stimulated O2.- formation during the protocol, both in the angina stable patients and healthy subjects.
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Background: Several alterations of polymorphonuclearleukocyte (PMN) function were found in alcoholic cirrhotics that may contribute to augmented susceptibility to infections.
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A high level of atmospheric particulate matter induces an increase in circulating polymorphonuclearleukocyte (PMN) counts and an increase in serum inflammatory cytokine levels.
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We also suggest that in this model polymorphonuclearleukocytes are not required for tissue necrosis.
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The major populations expanded are polymorphonuclearleukocytes and macrophages.
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N-cadherin was expressed mainly in polymorphonuclearleukocytes in PB.
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On the contrary, polymorphonuclearleukocytes or adherent mononuclear cells are not involved in such a cytotoxic activity.
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Decrease in number of circulating blood mononuclear cells and polymorphonuclearleukocytes was not changed by estradiol treatment.
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At death, the left kidneys were snap-frozen and immunohistologically stained for the presence of polymorphonuclearleukocytes and monocytes.
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After incubation of the cell walls and peptidoglycan with various opsonic sources, uptake by human polymorphonuclearleukocytes was measured.