The cellular toxicity of HNE-aSyn was significantly higher than other PTM species.
2
Protein arginine methylation is a PTM involved in various cellular processes in eukaryotes.
3
During follow-up no new PTM foci and no nodal metastases have been identified.
4
TGM2-mediated histaminylation is thus a novel PTM that functions in G protein signaling.
5
PTM supporters in Peshawar protested outside the Islamabad Press Club late on Sunday evening.
1
Mono-ADP-ribosylation is a reversible posttranslationalmodification that modulates the function of target proteins.
2
A total of 14 proteins had changes suggesting altered posttranslationalmodification.
3
Here, we describe a previously unknown posttranslationalmodification of the DNA-binding domain of p53.
4
Protein methylation is a common posttranslationalmodification that mostly occurs on arginine and lysine residues.
5
This enzyme catalyzes O-GlcNAcylation, a posttranslationalmodification that is influenced by the cellular metabolic state.
1
NEDDylation is a post-translationalproteinmodification that is tightly linked to ubiquitination and thereby protein degradation.
2
The versatility of ubiquitin in regulating protein function and cell behaviour through post-translationalproteinmodification makes it a particularly attractive target for viruses.
3
As glycosylation is the most common type of post-translationalproteinmodification, we are currently placing an emphasis on annotation of protein glycosylation in SWISS-PROT.
4
However, in contrast to other post-translationalproteinmodifications, S-nitrosylation is generally considered to be non-enzymatic, involving multiple chemical routes.
1
Conclusions: These results identify posttranslationalproteinmodification as of importance in chronic gut inflammation in humans.
2
Existing evidence indicates nitroalkenes support posttranslationalproteinmodifications and transcriptional activation that promote the resolution of inflammation.
3
Identification of MHC class II-restricted peptide epitopes from tumor-associated antigens including those generated from posttranslationalproteinmodifications should enable the improvement of peptide-based cancer immunotherapy.
Uso de post-translational modification en inglés
1
This post-translationalmodification stabilizes and increases the activity of this transcription factor.
2
O-GlcNAcylation is a key post-translationalmodification that modifies the functions of proteins.
3
This suggests that NNMT receives a post-translationalmodification in cancer- specific manner.
4
S-nitrosylation is becoming increasingly recognized as an important post-translationalmodification with signaling consequences.
5
Palmitoylation is a reversible, post-translationalmodification observed in a number of G-protein-coupled receptors.
6
The function of cMyBP-C is stringently regulated by its post-translationalmodification.
7
Interestingly, further investigation uncovers that heparin can also affect the post-translationalmodification of sFRP-1.
8
We hypothesized that the post-translationalmodification sumoylation fine-tunes channel activity.
9
Protein mono-ADP-ribosylation is a reversible post-translationalmodification of cellular proteins.
10
Tyrosine nitration is a nitric oxide-derived post-translationalmodification of proteins.
11
Cell cycle phase therefore regulates GR localisation and post-translationalmodification which selectively impacts GR activity.
12
Many aspects of translation are regulated by post-translationalmodification.
13
Tyrosine phosphorylation is a dynamic reversible post-translationalmodification that regulates many aspects of cell biology.
14
We earlier demonstrated that OAT3 is subjected to a specific type of post-translationalmodification called SUMOylation.
15
However, the contribution of co- and post-translationalmodification to SFKs activation has not been fully elucidated.
16
Farnesylation is an important post-translationalmodification essential for the proper localization and function of many proteins.