Both regions demonstrate similar relative DNase I sensitivities within a given tissue.
2
Using DNase-seq data improved predictions of tissue-specific expression compared with motifs alone.
3
The DNA nature of these filaments was determined by digestion with DNase.
4
DNase activity in the original seminal plasma was abolished after HFF co-incubation.
5
Nuclear GAPDH is tightly bound, resisting extraction by DNase or salt treatment.
1
Both regions demonstrate similar relative DNaseI sensitivities within a given tissue.
2
Precise binding regions were investigated by DNAseI protection studies.
3
In situ oligo ligation technique was used to identify specific DNaseI-type DNA cleavage.
4
Gel shift and DNaseI analyses demonstrated that IclR binds to its own promoter.
5
DNA-melting and DNaseI footprinting experiments were also performed.
Uso de rhdnase en inglés
1
We compared the effect of rhDNase and HS on cationic proinflammatory mediators in CF sputum.
2
In summary, we were unable to show that rhDNase or HS promote airway inflammation in CF.
3
When changes in mediator levels with daily rhDNase were compared with alternate-day rhDNase and HS, no significant differences were detected.
4
The double-blind, 14 day study showed no significant improvement in pulmonary function but some patients may have improved after longer administration of rhDNase.