Significados de selective inhibitor en inglés

Here we describe the structure-based design of a selective inhibitor of SKCa2.

Tivozanib is a potent and selective inhibitor of the VEGF receptor.

The CaMKII-induced inhibition was blocked by the selective inhibitor KN-62.

This is the first study to report a potent and selective inhibitor of mammalian elongases.

Bicyclomycin is the only known selective inhibitor of rho.

FX11 is a selective inhibitor of LDHA that has demonstrated preclinical efficacy in adult cancers.

Pharmacological inhibition of Axl using the selective inhibitor R428 had comparable effects in reducing migration and invasion.

Ranolazine is a selective inhibitor of the late sodium current in myocytes with anti-ischemic and metabolic properties.

The phosphorylation of rhodopsin by protein kinase C is inhibited by the protein kinase C- selective inhibitor sangivamycin.

Thus, galangin can be a promising candidate as a selective inhibitor to suppress phosphorylation of Smad3 linker region.

Daclatasvir is a first-in-class, potent, and selective inhibitor of the hepatitis C virus nonstructural protein 5A replication complex.

These data show that TBB is a quite selective inhibitor of CK2, that can be used in cell-based assays.

Testing its binding affinities against other bromodomain-containing proteins shows that 31 is a highly selective inhibitor of BET proteins.

Reported herein is the optimization of a nonselective scaffold into a potent and highly selective inhibitor of Tie-2 kinase.

Our previous work has shown thalidomide to be a relatively selective inhibitor of TNF-alpha production in vivo and in vitro.

BACKGROUND: Irinotecan is a selective inhibitor of topoisomerase I, an enzyme part of the replication and transcription system of DNA.