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1Here we describe the structure-based design of a selective inhibitor of SKCa2.
2Tivozanib is a potent and selective inhibitor of the VEGF receptor.
3The CaMKII-induced inhibition was blocked by the selective inhibitor KN-62.
4This is the first study to report a potent and selective inhibitor of mammalian elongases.
5Bicyclomycin is the only known selective inhibitor of rho.
6FX11 is a selective inhibitor of LDHA that has demonstrated preclinical efficacy in adult cancers.
7Pharmacological inhibition of Axl using the selective inhibitor R428 had comparable effects in reducing migration and invasion.
8Ranolazine is a selective inhibitor of the late sodium current in myocytes with anti-ischemic and metabolic properties.
9The phosphorylation of rhodopsin by protein kinase C is inhibited by the protein kinase C- selective inhibitor sangivamycin.
10Thus, galangin can be a promising candidate as a selective inhibitor to suppress phosphorylation of Smad3 linker region.
11Daclatasvir is a first-in-class, potent, and selective inhibitor of the hepatitis C virus nonstructural protein 5A replication complex.
12These data show that TBB is a quite selective inhibitor of CK2, that can be used in cell-based assays.
13Testing its binding affinities against other bromodomain-containing proteins shows that 31 is a highly selective inhibitor of BET proteins.
14Reported herein is the optimization of a nonselective scaffold into a potent and highly selective inhibitor of Tie-2 kinase.
15Our previous work has shown thalidomide to be a relatively selective inhibitor of TNF-alpha production in vivo and in vitro.
16BACKGROUND: Irinotecan is a selective inhibitor of topoisomerase I, an enzyme part of the replication and transcription system of DNA.
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Selective inhibitor ao longo do tempo
Selective inhibitor nas variantes da língua
Estados Unidos da América