Factors that control recruitment of thecacells from ovarian stromal-interstitial cells are important for early follicle development in the ovary.
2
During recruitment, thecacells organize into distinct layers around early developing follicles and establish essential cell-cell interactions with granulosa cells.
3
Recruitment of thecacells from ovarian stromal stem cells is proposed to involve cellular proliferation, as well as induction of theca cell-specific functional markers.