We identified candidate pools of epigenetic compounds that improve skeletal muscle structure in dmd mutant zebrafish.

Results: We performed a novel chemical-combination screen of a library of epigenetic compounds using the zebrafish dmd model.

A commercially available library of epigenetic small molecules was used to treat embryonic-larval stages of dmd mutant zebrafish.

Methods: Eight families at risk for DMD were recruited for this study.

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