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Meanings of mdr gene in inglês
We have no meanings for "mdr gene" in our records yet.
Usage of mdr gene in inglês
1
The mammalian mdrgene family comprises a small number of closely related genes.
2
Expression levels of each mdrgene are dramatically different in various mouse tissues.
3
We have identified distinct mdrgene transcripts encoded by three separate mdr genes in the mouse.
4
In this report, we characterize a second member of the mdrgene family which we designated mdr2.
5
Alternatively, some groups are investigating transfecting the mdrgene into bone marrow cells to reduce the sensitivity of these cells to cytotoxic agents.
6
Each of the mdrgenes has a specific RNA transcript pattern.
7
Thus, determination of MDRgene expression at diagnosis appears likely to provide useful prognostic information for acute leukemia patients.
8
Recent studies have suggested the potential involvement of genes in the MDRgene family in resistance to quinoline-containing compounds in P. falciparum.
9
Multidrug resistance in mammalian tumor cells is associated with the overexpression of mdrgenes encoding P-glycoproteins, which function as drug efflux pumps.
10
Collectively, these results indicate that de-differentiated cells up-regulate MDRgenes via PERK-Nrf2 signaling and suggest that targeting this pathway could sensitize drug-resistant cells to chemotherapy.