Significados de network hub em inglês

The network hub is at Tralee IT.

Systems analysis identified the exocyst complex as a key network hub, rich in genetic interactions with endocytic and exocytic components.

We found that the network hub gene Bcat1 and seven other co-regulated MMnet genes out of 13, regulate bone function.

As an interface, the anterior insula (AI) has recently been shown to be a network hub, which initiates dynamic switching between these intrinsic networks.

Conclusions: Interestingly, we find that lncRNA network hubs tend to be significantly enriched in evolutionary conserved lncRNAs and enhancer-like functions.

The transcription factors also formed network hubs with genes from other functional categories, thus allowing regulation of one functional pathway through manipulation of another.

Results: Compared to controls, patients with schizophrenia and the high risk subjects showed significantly weakened network hubs in left inferior frontal and right fusiform gyri.

This work has highlighted the general importance of network hubs as hotspots for concentration of cortical grey-matter deficits in schizophrenia, Alzheimer's disease and other disorders.