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Significados de secretory granule em inglês
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.
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Uso de secretory granule em inglês
1
Thus the secretory granule-specific sulfated molecule is a proteoglycan with chondroitin sulfate side chains.
2
The molecular mechanisms governing secretory granule maturation are largely unknown.
3
This process is mediated by secretory granule exocytosis.
4
The single secretory granule of the sperm fuses at multiple points with the overlying plasma membrane.
5
We further demonstrate that HID-1 deficiency prevented secretory granule maturation by blocking homotypic fusion of immature secretory granules.
6
Presumably all of the proteins secreted by the regulated secretory granule pathway share some common property that targets them to the secretory granule.
7
Here, we show that excess granules evading exocytosis are degraded via direct fusion with lysosomes, a secretory granule-specific autophagic process known as crinophagy.
8
However, the molecular steps that regulate secretory granule movement and membrane fusion as well as the role of the cytoskeleton are still poorly understood.
9
Prolactin and galanin colocalize in the same secretory granule, the expression of both proteins is extremely sensitive to the estrogen status of the animal.
10
These findings suggest a role for Munc18-2 and the microtubule network in the regulation of secretory granule dynamics in mast cells.
11
Ultrastructurally, the cytoplasm of the tumor cells contained various sized secretory granules.
12
Thus, the composition of secretions from individual secretory granules is regulated.
13
The vesicles were identified as secretory granules by their content in immunoreactive serotonin.
14
Morphological analysis revealed the presence of intact chromaffin cells with well-preserved secretory granules.
15
Ciliated cells are characterized with light and dense secretory granules in supernuclear cytoplasm.
16
Our data identify a novel player during the early maturation of immature secretory granules.