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Methods: We undertook unsupervised analyses of RNA-sequencing data of 284 MPMs, with no assumption of discreteness.
2
Small replicate numbers, discreteness, large dynamic range and the presence of outliers require a suitable statistical approach.
3
We utilize the discreteness of Dirichlet process prior to cluster signatures that exhibit similar differential expression profiles.
4
The permutation test performs well for any settings though the discreteness in cluster size must be accounted for.
5
The discreteness is still more obvious when, instead of old things changing, they cease, or when altogether new things come.
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And if speciation unfolds in geological moments, then species in geological time match organisms on our ordinary yearly scales in both distinctness and discreteness.
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But, by important contrast, species construct their equally powerful integrity and discreteness by different means that do not require such suppression of upwardly cascading effects.
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But its apparent discreteness is due to a failure to distinguish between the silent, unobtrusive working of comparison and the more obvious and self-conscious working.