Мы используем Cookies Этот веб-сайт использует cookie-файлы, чтобы предлагать вам наиболее актуальную информацию. Просматривая этот веб-сайт, Вы принимаете cookie-файлы.
Resistance to tumor necrosis factor-related apoptosis- inducingligand (TRAIL) is a major limitation for its clinical use.
3
Here we describe a novel member of the TNF family designated APRIL (for a proliferation- inducingligand).
4
A proliferation- inducingligand (APRIL) is a new tumor necrosis factor family member implicated in tumor cell proliferation.
5
Background: Tumor necrosis factor-related apoptosis- inducingligand (TRAIL) induces apoptosis in malignant cells but not in normal cells.
6
Purpose: B-lymphocyte stimulator and a proliferation- inducingligand regulate B-cell homeostasis and immunoglobulin production and are overexpressed in B-cell malignancies.
7
Tumor necrosis factor-related apoptosis inducedligand (TRAIL) is an important apoptosis inducer in a variety of tumor cells.
8
ER stress induces the upregulation of tumor necrosis factor-related apoptosis inducingligand (TRAIL) receptor and opening new horizons for therapeutic research.
9
TNF-related apoptosis- inducingligand (TRAIL) is a type II integral membrane protein that interacts with multiple receptors and cell types including neurons.
10
In addition, overexpression of RTVP-1 rendered glioma cells more resistant to the apoptotic effect of tumor necrosis factor-related apoptosis- inducingligand and serum deprivation.
11
Here we show that tumor necrosis factor-related apoptosis- inducingligand (TRAIL) plays a critical role in the NK cell-mediated and IFN-gamma-dependent tumor surveillance.
12
We have previously reported tumor necrosis factor-related apoptosis- inducingligand (TRAIL) immunoreactivity within pulmonary vascular lesions from patients with idiopathic PAH and animal models.
13
One such anti-neoplastic protein is tumour necrosis factor-related apoptosis- inducingligand (TRAIL) because it induces apoptosis in cancerous cells, but not in non-transformed cells.
14
Tumor necrosis factor-related apoptosis- inducingligand (TRAIL), a tumor necrosis factor superfamily member, targets death receptors and selectively kills malignant cells while leaving normal cells unaffected.