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Agreement was measured using weighted kappa analysis for ordinaldata.
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Importantly, DIRAC can be applied not only to transcriptomic data, but to any ordinaldata type.
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Comparison of the two treatment arms was done using methods for longitudinal quantitative and longitudinal ordinaldata.
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The data were then reconstructed and analyzed using ordinaldata full information maximum likelihood in the OpenMx program.
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Independent t-test, Chi-square, and Mann-Whitney U test evaluated the significance for continuous parametric, dichotomous, and ordinaldata, respectively.
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Their relative performance for the longitudinal ordinaldata setting under the missing at random (MAR) assumption is not well documented.