Last month Biogen said a fourth patient in Europe had developed PML.
2
However, the basis for such a structural role of PML is unknown.
3
The average number of infusions received before diagnosis of PML was 25.
4
In particular, PML and p53 showed considerable potential as independent prognostic markers.
5
Dozens of patients undergoing treatment with Tysabri have been diagnosed with PML.
1
Allogeneic and peptide vaccines and granulocyte-macrophage colony-stimulating factor are also being evaluated.
2
However, the increase of expression level varied among the PBSC and granulocyte products.
3
Results: Fifty-one transcripts were chosen to be preferentially expressed by each granulocyte subtype.
4
The binding curve data suggested that there are two monocyte and granulocyte populations.
5
These antibodies are directed against different enzymes located in granulocyte granules.
1
Mature granulocytes show a markedly limited life span and rapidly undergo apoptosis.
2
So they took Anna in to give granulocytes -white blood cells.
3
To resolve infections, an adequate number of functional granulocytes is required.
4
With few exceptions, treatment resulted in a prompt increase in granulocytes and eosinophiles.
5
These studies indicate that bcl-2 is involved in regulating apoptosis in maturing granulocytes.
1
In contrast, lipid A was a potent inducer of the PMNL response.
2
The studies reported here were undertaken to determine whether influenza virus could replicate within PMNL.
3
Both host- and virus-specific proteins were produced within PMNL.
4
Conclusion: Activated PMNLs enhance production of leukocyte MPs with increased adhesion molecules in patients with sepsis.
5
This study analyzed the ability of mucosally administered bacterial components to activate IL-6 and PMNL responses.
1
Similar shifts were seen in the graphs of polymorphonuclearleukocyte elastase and thrombin-antithrombin complex.
2
Total white blood cell, polymorphonuclearleukocyte, and immature neutrophil counts rose significantly in response to sepsis.
3
Peripheral blood mature and immature polymorphonuclearleukocyte (PMN) cell counts were determined on Wright-stained blood smears.
4
Analysis of variance indicated that the means for polymorphonuclearleukocyte and immature neutrophil counts were significantly higher in survivors.
5
It has not been shown, however, that the polymorphonuclearleukocyte increase caused by nuclein has made phagocytosis more active.
1
Both polymorphonuclearcell infiltration and increased epithelial apoptosis are seen in gastric mucosa in the presence of Helicobacter pylori infection.
2
However, the chemotactic response of both polymorphonuclearcells and T lymphocytes in response to CXCL12 is increased.
3
H. pylori colonization is followed by infiltration of the gastric mucosa by polymorphonuclearcells, macrophages and lymphocytes.
4
The outcome of CDAD was not influenced by the number of circulating polymorphonuclearcells and CD4+ cells.
5
Polymorphonuclearcells (neutrophils) play an important role in the systemic inflammatory response syndrome and the development of sepsis.
Ús de pmn en anglès
1
The IC preparation did also induce an oxidative burst response in PMNs.
2
The circulating PMN of control subjects did not show a spontaneous O2-.
3
Despite this adaptation, their bactericidal capability remains limited when compared with PMNs.
4
To induce apoptosis PMNs were cultured overnight while Jurkat cells were UV-treated.
5
Conclusions: CPB primes the inflammatory system causing pulmonary PMN sequestration without lung injury.
6
In the centrally healed area neither SKALP expression nor PMN accumulation was shown.
7
Conclusions: PMN function of welders is lower than that of controls.
8
Moreover, bacteria-stimulated PMN recruitment and osteoclastogenesis were also dependent upon the host response.
9
For the isolation of PR-3 large numbers of PMNs are needed.
10
In each case PMN adhesion was sensitive to the tyrosine kinase inhibitor genistein.
11
Activated PMNs damage microcirculation or hepatocytes depending on the nature of the activation.
12
Preincubation in serum from patients with blastomycosis decreased the adherence of control PMN.
13
L-carnosine did not have any effects on IL-8 production or PMN-endothelial cell interactions.
14
By scanning electron microscopy, PMNs from air-exposed rats had features of non-motile cells.
15
PMNs were incubated with pH-adjusted test fluids for 30 minutes.
16
Apoptotic cells (PMNs and valvular cells) were abundantly detected in this area.