Last month Biogen said a fourth patient in Europe had developed PML.
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However, the basis for such a structural role of PML is unknown.
3
The average number of infusions received before diagnosis of PML was 25.
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In particular, PML and p53 showed considerable potential as independent prognostic markers.
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Dozens of patients undergoing treatment with Tysabri have been diagnosed with PML.
1
Allogeneic and peptide vaccines and granulocyte-macrophage colony-stimulating factor are also being evaluated.
2
However, the increase of expression level varied among the PBSC and granulocyte products.
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Results: Fifty-one transcripts were chosen to be preferentially expressed by each granulocyte subtype.
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The binding curve data suggested that there are two monocyte and granulocyte populations.
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These antibodies are directed against different enzymes located in granulocyte granules.
1
The IC preparation did also induce an oxidative burst response in PMNs.
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The circulating PMN of control subjects did not show a spontaneous O2-.
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Despite this adaptation, their bactericidal capability remains limited when compared with PMNs.
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To induce apoptosis PMNs were cultured overnight while Jurkat cells were UV-treated.
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Conclusions: CPB primes the inflammatory system causing pulmonary PMN sequestration without lung injury.
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Mature granulocytes show a markedly limited life span and rapidly undergo apoptosis.
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So they took Anna in to give granulocytes -white blood cells.
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To resolve infections, an adequate number of functional granulocytes is required.
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With few exceptions, treatment resulted in a prompt increase in granulocytes and eosinophiles.
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These studies indicate that bcl-2 is involved in regulating apoptosis in maturing granulocytes.
1
Similar shifts were seen in the graphs of polymorphonuclearleukocyte elastase and thrombin-antithrombin complex.
2
Total white blood cell, polymorphonuclearleukocyte, and immature neutrophil counts rose significantly in response to sepsis.
3
Peripheral blood mature and immature polymorphonuclearleukocyte (PMN) cell counts were determined on Wright-stained blood smears.
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Analysis of variance indicated that the means for polymorphonuclearleukocyte and immature neutrophil counts were significantly higher in survivors.
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It has not been shown, however, that the polymorphonuclearleukocyte increase caused by nuclein has made phagocytosis more active.
1
Both polymorphonuclearcell infiltration and increased epithelial apoptosis are seen in gastric mucosa in the presence of Helicobacter pylori infection.
2
However, the chemotactic response of both polymorphonuclearcells and T lymphocytes in response to CXCL12 is increased.
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H. pylori colonization is followed by infiltration of the gastric mucosa by polymorphonuclearcells, macrophages and lymphocytes.
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The outcome of CDAD was not influenced by the number of circulating polymorphonuclearcells and CD4+ cells.
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Polymorphonuclearcells (neutrophils) play an important role in the systemic inflammatory response syndrome and the development of sepsis.
Ús de pmnl en anglès
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In contrast, lipid A was a potent inducer of the PMNL response.
2
The studies reported here were undertaken to determine whether influenza virus could replicate within PMNL.
3
Both host- and virus-specific proteins were produced within PMNL.
4
Conclusion: Activated PMNLs enhance production of leukocyte MPs with increased adhesion molecules in patients with sepsis.
5
This study analyzed the ability of mucosally administered bacterial components to activate IL-6 and PMNL responses.
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A significant correlation was found between the number of infected PMNLs and the number of infected HELF cells.
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However, we also found interactions between the effects of haplotype and biopsy for body temperature, heart rate, and PMNL.
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Negative PCR results for PMNL after antiviral therapy indicate recovery, and fewer unwanted positive results occur compared to PBMC and plasma.
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By using indirect immunofluorescence techniques combined with flow cytometry, the expression of newly synthesized viral antigens was detected in virus-infected PMNL.
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Treatment was discontinued only after disappearance of IEA-positive PMNLs from blood (the last marker of infection to become negative).
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In conclusion, the measurement of transport of 3OMG in PMNLs may be useful for the study of glucose transport in clinical investigations.
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However, overall interpretation of the transcriptome data agreed in part with literature documenting a potentially detrimental, chronic activation of PMNL in response to overfeeding.
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Plaque assays on supernatant fluid from infected PMNL showed that infectious progeny were not produced, indicating that influenza virus infection of PMNL is abortive.
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Blood for PMNL isolation and metabolite analysis was collected at -14 and +7 days relative to parturition.