Aún no tenemos significados para "randomize trials".
1Randomized trials that compare new drugs with current standard treatments are needed.
2Methods: We conducted a systematic review of published and unpublished randomized trials.
3Results: Six randomized trials and two published meta-analyses of follow-up were obtained.
4Results obtained in randomized trials may not easily generalize to target populations.
5Randomized trials of sequenced biochemotherapies should shed further light on this issue.
6Randomized trials should evaluate whether PCI could improve survival of advanced LCNECs.
7Several randomized trials of androgen supplementation in older men have been undertaken.
8These preliminary findings from this uncontrolled study require confirmation in randomized trials.
9Few randomized trials have been performed to evaluate other CAM fertility treatments.
10Eligible studies include randomized trials with bevacizumab in patients with breast cancer.
11This conclusion needs to be confirmed by future large randomized trials.
12Bias against publishing nonsignificant results is a problem even for large randomized trials.
13Prospective, randomized trials are needed to firmly assess this possible difference.
14Results: Of ten randomized trials identified, five were considered for analysis.
15Data synthesis: Twenty-eight articles from 26 randomized trials met eligibility criteria.
16Ongoing randomized trials of selenium supplements may help to further evaluate this issue.