Usage of "gene deletion"

A mutation in which a part of a chromosome or a sequence of DNA is missing.

Uso de gene deletion em inglês

A dual guide approach improved gene deletion efficacy in both cell types. 
 Pubmed 

CHOP gene deletion in SCs decreased cell death in response to TNF-a. 
 Pubmed 

Quantitative polymerase chain reaction indicated total WASP gene deletion in the proband. 
 Pubmed 

Aromatase gene deletion in female mice exacerbates ischemic brain damage after stroke. 
 Pubmed 

In addition, essential genes were predicted via single gene deletion studies. 
 Pubmed 

Gao was specifically inactivated in pancreatic progenitor cells by pancreatic cell-specific gene deletion. 
 Pubmed 

Lrh-1 gene deletion attenuates cancer cell metabolism in hepatocytes through mitochondrial glutamine processing. 
 Pubmed 

Determining the effect of gene deletion is a fundamental approach to understanding gene function. 
 Pubmed 

The specific inhibitors and gene deletion technologies were used to address the molecular mechanisms. 
 Pubmed 

CLIC4 gene deletion markedly attenuated the development of chronic hypoxia-induced pulmonary hypertension in mice. 
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In this study, we used gene deletion and complement methods to confirm its putative functions. 
 Pubmed 

Conclusion: NOS2 gene deletion did not affect the inflammatory responses, but reduced the cartilage degradation. 
 Pubmed 

Targeted gene deletion in the producer resulted in a 90% reduced diaminopentane secretion. 
 Pubmed 

Methods: We studied a twin pair with an exon 4 gene deletion in the PGRN gene. 
 Pubmed 

Recently, gene deletion revealed a predominant role of NPR-B in endochondral ossification and development of female reproductive organs. 
 Pubmed 

Thus, our findings show that ubiquitous CSF-1 gene deletion using a Cre-based system recapitulates the expected osteopetrotic phenotype. 
 Pubmed 

Significados de gene deletion em inglês