Значения для термина "conserve residue" отсутствуют.
1 Protein-altering mutations were significantly enriched for changes at highly conserved residues .
2 Other conserved residues act sterically to provide a structural basis for polyamine specificity.
3 Mutational studies of these conserved residues highlight their functional importance.
4 All variants affect highly conserved residues in the SCN5A protein.
5 Most pathological missense mutations in human L1 affect conserved residues .
6 We also demonstrate the importance of these conserved residues for proteolysis by an archaeal proteasome.
7 The variants disrupt highly conserved residues across the protein.
8 In contrast, the E2 protein's transactivation domain does not have extensive surfaces of highly conserved residues .
9 Here, we investigate the extent to which these conserved residues are clustered in three-dimensional protein structures.
10 To assess the significance of conserved residues , various point mutations and deletions were introduced into this region.
11 This protein contains all but one conserved residues known to be involved in beta-galactoside binding in galectins.
12 These results suggested that the conserved residue Tyr-194 is critical for catalytic function of the novel AHL-lactonase.
13 Conserved residues from all three monomers contribute to each of the three active sites within the dUTPase.
14 Therefore, detection of the conserved residues using phylogenetic analysis is a general approach to predict functionally critical residues.
15 KCNJ8-S422L involves a highly conserved residue and was absent in 1,200 reference alleles.
16 BRIP1 p.R848H alters a highly conserved residue in the catalytic DNA helicase domain.
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