A pattern of expression of a set of genes whose products somehow contribute to a function in a cell or organism.
Синонимы
Examples for "program"
Examples for "program"
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Unfortunately, the program doesn't quite work in the way the producers intended.
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How a rogue weapons program created the new American way of war.
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The program faced criticism even before the health reform law was passed.
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Backers hope to expand the program to 50 countries within five years.
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Singapore Airlines will join the test program later this year, it said.
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TBI modulates the neuronal excitability resulting in propagation of a neuronal activity-driven gene expression program.
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All living creatures change their gene expression program in response to nutrient availability and metabolic demands.
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Our study provides molecular-level understanding of a gene expression program in B. abortus that is downstream of σE1.
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Notch induces a broad antiapoptotic gene expression program that protects against intrinsic, as well as extrinsic, apoptosis pathways.
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Together, these findings indicate that Setd1b serves as maternal effect gene through regulation of the oocyte gene expression program.
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However, the heart retains the ability to return to the "fetal" gene program.
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Despite the advance, there is no therapy available to reverse the already committed gene program.
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In contrast, exposure to arterial laminar flow induces a gene program that confers a largely antiadhesive, antithrombotic effect.
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Finally, real-time quantitative PCR revealed an age-dependent recapitulation of the fetal gene program, consistent with a myopathic process.
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Finally, we show that OXT acts directly on OXTRs on adipocytes to suppress the white-to-beige transition gene program.
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The genetic program for the development of the TMJ remains poorly understood.
2
It must have been a genetic program, but officially he's an accident.
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For Wilson, the genetic program is key to understanding human development on all levels.
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The survival and death of lymphoid cells is under the control of a genetic program.
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Conclusion: LKB1 and Notch share a common genetic program in the liver, and regulate bile duct morphogenesis.
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Mitotic phosphorylation of YAP controls a unique transcriptional program in pancreatic cells.
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These results define a transcriptional program that controls diversification of a paramorphic pair.
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STAT3 hijacks a subset of ER enhancers to drive a distinct transcriptional program.
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HOTAIR overexpression is sufficient to activate the ER transcriptional program even under hormone-deprived conditions.
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The cellular response to hypoxia relies on the activation of a specific transcriptional program.
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This reconstruction allowed us to identify candidate regulatory gene circuit elements underlying T cell fate decision making.
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Using a synthetic gene circuit, we show that a transcriptional activator driven by yeast cell-cycle promoters propagates transcriptional oscillations with substantial damping.
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Regulatory gene circuits enable stem and progenitor cells to detect and process developmental signals and make irreversible fate commitment decisions.
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Accurately predicting noise propagation in gene networks is crucial for understanding signal fidelity in natural networks and designing noise-tolerant gene circuits.
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The ability to create designer aTFs will enable applications including dynamic control of cell metabolism, cell biology and synthetic gene circuits.
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Further, P-HIPSTer enables discovery of previously unappreciated cellular circuits that act on human-infecting viruses and provides insight into experimentally intractable viruses.
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It is envisaged that analysing the cellular 'circuitry' of ongoing molecular networks will become a powerful clinical tool in patient management.
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Tongue myogenesis follows a similar regulatory program to that for limb myogenesis.
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In January 2013, U.S. District Court Judge James Boasberg issued an injunction halting the IRS's regulatory program.
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The analysis of time course data on cell differentiation indicated a shift in the regulatory program associated with Pioneer-like transcription factors during differentiation.
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Despite recent advances in our understanding of the gene regulatory program directing steatosis, how it is orchestrated at the chromatin level is unclear.
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Comparison of medulloblastoma regulatory elements with those of the developing brain reveals that these tumors engage a developmental regulatory program to drive OTX2 transcription.
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What is less clear is how these changes interact with trans-acting changes occurring elsewhere in the genetic circuit.
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In a normal cell, powerful genetic circuits regulate cell division and cell death.
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We found 364 candidate obesity-regulating cis elements and genetic circuits in different cell types.
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Cells act like tiny computers, and finally, scientists are figuring out what makes their genetic circuits blink on and off.
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This finding leads to the proposal that mathematicians study genetic circuits to find new geometries for which structure theorems may exist.
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Now that they've gotten these basic genetic circuits to work, the next step is to make the logic gates work in different types of cells.
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A combined analysis of these functional and regulatory ILP interactions identifies local genetic circuits that act in parallel and interact by crosstalk, feedback and compensation.