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We compared the effect of rhDNase and HS on cationic proinflammatory mediators in CF sputum.
2
In summary, we were unable to show that rhDNase or HS promote airway inflammation in CF.
3
When changes in mediator levels with daily rhDNase were compared with alternate-day rhDNase and HS, no significant differences were detected.
4
The double-blind, 14 day study showed no significant improvement in pulmonary function but some patients may have improved after longer administration of rhDNase.
1
Both regions demonstrate similar relative DNaseI sensitivities within a given tissue.
2
Precise binding regions were investigated by DNAseI protection studies.
3
In situ oligo ligation technique was used to identify specific DNaseI-type DNA cleavage.
4
Gel shift and DNaseI analyses demonstrated that IclR binds to its own promoter.
5
DNA-melting and DNaseI footprinting experiments were also performed.
Usage of dnase in English
1
Both regions demonstrate similar relative DNase I sensitivities within a given tissue.
2
Using DNase-seq data improved predictions of tissue-specific expression compared with motifs alone.
3
The DNA nature of these filaments was determined by digestion with DNase.
4
DNase activity in the original seminal plasma was abolished after HFF co-incubation.
5
Nuclear GAPDH is tightly bound, resisting extraction by DNase or salt treatment.
6
Majority of cells showed DNA fragmentation specific to caspase-3-activated DNase I.
7
We then mined DNase-seq data to identify putative active CRMs and TF footprints.
8
Addition of HFF to seminal plasma appeared to inhibit DNase activity.
9
Precise binding regions were investigated by DNAse I protection studies.
10
In situ oligo ligation technique was used to identify specific DNase I-type DNA cleavage.
11
DNase digestion and fragment size determination studies were used to characterize the DNA detected.
12
Gel shift and DNase I analyses demonstrated that IclR binds to its own promoter.
13
We have recently described a protocol to generate a genome-wide library of DNase HS sites.
14
DNA-melting and DNase I footprinting experiments were also performed.
15
Results: In the present study, we investigated the expression of the homologous DNase in P. knowlesi.
16
Results of DNase I footprinting provide strong support for bent recognition helices in leucine zipper protein-DNA complexes.